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Most synthetic cannabinoids are agonists of the cannabinoid receptors. They are designed to be similar to THC,[nine] the purely natural cannabinoid Using the strongest binding affinity for the CB1 receptor, and that is linked to the psychoactive consequences or "high" of marijuana.[ten] These synthetic analogs normally have greater binding website affinity and greater potency towards the CB1 receptors.
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Synthetic Cannabinoids are illegal in New Zealand, it is classified as a category A controlled drug.[198] The New website Zealand Parliament handed a law in July 2013 banning the sale of legal highs in dairies and supermarkets, but letting some "minimal risk" medicine to continue to get bought by way of speciality certified outlets.
The situation of David Mitchell Rozga, an American teenager from Indianola, Iowa, introduced Global notice to K2. Rozga shot himself in The top using a loved ones-owned looking rifle in an obvious suicide on June six, 2010. Soon after news of Rozga's Dying, it absolutely was documented by good friends which they had smoked K2 with Rozga somewhere around one particular hour before his Loss of life. The character of his Dying and reports from many close relatives, led investigators to suspect that Rozga was beneath the affect of the brain-altering material when he died.
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